The key fixture in the battle for a top-four place takes place at 14:00 GMT.
United lie third in the Premier League table, level on points with the Midlanders, after slipping up at Newcastle United last time out.
The visitors had a UEFA Europa League assignment at Lille on Thursday, which they won 1-0.
The good news is Mason Mount makes a welcome return to the squad, after being absent since the Manchester derby win over City on 17 January, when he was unlucky to have a late goal ruled out.